{"id":9,"date":"2025-02-24T20:46:33","date_gmt":"2025-02-24T20:46:33","guid":{"rendered":"https:\/\/osre.dk\/ar\/?page_id=9"},"modified":"2025-12-19T07:26:28","modified_gmt":"2025-12-19T07:26:28","slug":"dos","status":"publish","type":"page","link":"https:\/\/osre.dk\/ar\/","title":{"rendered":"dOs"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull is-light has-contrast-color has-text-color has-link-color wp-elements-617ad7fcb6ea57ac2568f18930148180\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--50)\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-base-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-container-core-cover-is-layout-873ee6b1 wp-block-cover-is-layout-constrained\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-7ee84d44 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:65%\">\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-353c4f5a wp-block-group-is-layout-flex\">\n<h2 class=\"wp-block-heading has-text-align-left\" style=\"font-size:clamp(1.502rem, 1.502rem + ((1vw - 0.2rem) * 1.565), 2.5rem);font-style:normal;font-weight:300;letter-spacing:-0.03em;line-height:1.4\">Prof. Damjan Osredkar, MD, PhD<\/h2>\n\n\n\n<p class=\"is-style-default\">Head of the Department of Pediatric Neurology at the University Children&#8217;s Hospital in Ljubljana, Slovenia.<\/p>\n\n\n\n<p class=\"is-style-default\">I am interested in clinical work and research in the field of pediatric neurology, particularly neuromuscular diseases, rare diseases and neuroprotection after hypoxic-ischemic brain injury. Finding new ways to help patients and possibly cure them of their diseases motivates our team and myself.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Research Interests<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Rare diseases (CTNNB1 Syndrome, SAS \/ SATB2, PIK3CA)<\/li>\n\n\n\n<li>Neuromuscular diseases\n<ul class=\"wp-block-list\">\n<li>Spinal muscular atrophy<\/li>\n\n\n\n<li>Duchenne muscular dystrophy<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Novel treatment options<\/li>\n\n\n\n<li>Gene replacement therapy<\/li>\n\n\n\n<li>Neuroprotective treatment<\/li>\n\n\n\n<li>Neural enhancement<\/li>\n\n\n\n<li>Hypothermia treatment<\/li>\n\n\n\n<li>Brain energy metabolism<\/li>\n\n\n\n<li>Electroencephalography (Conventional and amplitude-integrated)<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Positions Held<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2015 &#8211; Present:<\/strong> Head of the Pediatric Neurology Department, University Children&#8217;s Hospital, University Medical Centre Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2025 &#8211; Present:<\/strong> Full Professor of Pediatrics, Medical Faculty, University of Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2007 &#8211; Present:<\/strong> Physician, Department of Pediatric Neurology, University Children&#8217;s Hospital, University Medical Centre Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2012 &#8211; 2014:<\/strong> Postdoctoral Fellow &amp; Guest Researcher, University of Oslo, Norway<\/li>\n\n\n\n<li><strong>2013 &#8211; 2014:<\/strong> Guest Pediatric Neurologist, Oslo University Hospital (Rikshospitalet), Norway<\/li>\n\n\n\n<li><strong>2007 &#8211; 2009:<\/strong> Postdoctoral Fellow, University of California, San Francisco, USA<\/li>\n\n\n\n<li><strong>2003 &#8211; 2004:<\/strong> Guest Researcher, UMC Utrecht, The Netherlands<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Education<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2007:<\/strong> Specialization in Pediatrics, University Medical Centre Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2006:<\/strong> PhD, University of Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2003:<\/strong> MSc, University of Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>1999:<\/strong> MD, University of Ljubljana, Slovenia<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Awards \/ Grants<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2023:<\/strong> <a>Acknowledgments of the Medical Association of Slovenia &#8211; Working Group for Managing Screen Time in Children and Adolescents<\/a><\/li>\n\n\n\n<li><strong>2009:<\/strong> <a href=\"http:\/\/great.ucsf.edu\/great-people-awardees-june-2009\">UCSF Great People Award<\/a><\/li>\n\n\n\n<li><strong>2007:<\/strong> <a href=\"http:\/\/www.cies.org\/about_fulb.htm\">Fulbright Scholarship<\/a><\/li>\n\n\n\n<li><strong>2006:<\/strong> <a href=\"http:\/\/pednevro.pedkl.si\/wp-content\/uploads\/2008\/06\/2007.01.sinfo.adfutura.pdf\">Best Thesis Award &#8220;Futurum&#8221;, Ad Futura<\/a><\/li>\n\n\n\n<li><strong>2003:<\/strong> Huygens Grant (Funded by Dutch Government)<\/li>\n\n\n\n<li><strong>2001:<\/strong> Educational Grant (International Atomic Energy Agency, IAEA)<\/li>\n\n\n\n<li><strong>1997:<\/strong> Pre\u0161ern&#8217;s Prize for Student Research, Medical Faculty, University of Ljubljana<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Founder \/ Cofounder<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2017 &#8211; Present:<\/strong> <a href=\"http:\/\/hopnagrad.si\">Hop na Grad<\/a> \u2013 A fundraising event supporting children at University Children&#8217;s Hospital in Ljubljana, Slovenia<\/li>\n\n\n\n<li><strong>2011 &#8211; 2015:<\/strong> <a href=\"http:\/\/lublana.si\">Lublana<\/a> \u2013 A website promoting local communities, social connections, and art in Ljubljana<\/li>\n\n\n\n<li><strong>2006:<\/strong> <a href=\"http:\/\/www.medenosrce.net\/\">Medeno Srce<\/a> \u2013 A platform for exchanging study materials among medical students at the University of Ljubljana<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Memberships<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2011 &#8211; Present:<\/strong> European Neonatal Brain Club<\/li>\n\n\n\n<li><strong>2008 &#8211; Present:<\/strong> Society for Neuroscience<\/li>\n\n\n\n<li><strong>2006 &#8211; Present:<\/strong> Sinapsa &#8211; Slovenian Neuroscience Association (Founding Member)<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Projects<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Ongoing Projects<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2022 \u2013<\/strong> <a href=\"https:\/\/db.cngb.org\/mmhp\/\">Million Microbiomes from Humans Project<\/a> <em>(Collaborator)<\/em><\/li>\n\n\n\n<li><strong>2022 \u2013<\/strong> SERAPTA MIS51ON study <em>(Principal Investigator of the Slovenian site)<\/em><\/li>\n\n\n\n<li><strong>2022 \u2013<\/strong> PTC Stride registry: Long Term Observational Study of Translarna Safety and Effectiveness in Usual Care (PTC124 GD 025o DMD) <em>(Principal Investigator of the Slovenian site)<\/em><\/li>\n\n\n\n<li><strong>2021 \u2013<\/strong> <a>Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation (Gen-Phe CTNNB1)<\/a> <em>(Principal Investigator)<\/em><\/li>\n\n\n\n<li><strong>2021 \u2013<\/strong> ActiMyo\u00ae device: Monitoring of daily activity levels of patients with neuromuscular diseases <em>(Principal Investigator of the Slovenian site)<\/em><\/li>\n\n\n\n<li><strong>2019 \u2013<\/strong> Collaboration in European centralised registry of patients with spinal muscular atrophy <em>(Research project; Principal Investigator together with Bla\u017e Kortinik)<\/em><\/li>\n\n\n\n<li><strong>2012 \u2013<\/strong> Applied and Basic Physiology and Pathophysiology in Medicine, Slovenian Research Agency <em>(Collaborator; Principal Investigator: Du\u0161an \u0160uput)<\/em><\/li>\n\n\n\n<li><strong>2009 \u2013<\/strong> SCPE-NET: Surveillance of Cerebral Palsy in Europe, EU Programme HEATLH \u2013 EAHC <em>(Collaborator; Head Coordinator: Javier de la Cruz, Spain)<\/em><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">Completed Projects<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2016 \u2013 2018<\/strong> Cardio-respiratory responses during hypoxic exercise in individuals born prematurely, Slovenian Research Agency <em>(Research project; Principal Investigator)<\/em><\/li>\n\n\n\n<li><strong>2009 \u2013 2012<\/strong> Health risks of mercury on early development, Slovenian Research Agency <em>(Collaborator; Principal Investigator: David Neubauer, Slovenia)<\/em><\/li>\n\n\n\n<li><strong>2009 \u2013 2013<\/strong> Metabolic and in-born factors of reproductive health, Slovenian Research Agency <em>(Collaborator; Principal Investigator: \u017diva Novak Antoli\u010d, Slovenia)<\/em><\/li>\n\n\n\n<li><strong>2009 \u2013 2011<\/strong> NOTE: On-Line Training in Neonatology, European Lifelong Learning Programme \u2013 Leonardo da Vinci Actions <em>(Collaborator; Head Coordinator: Mike Hall, UK)<\/em><\/li>\n\n\n\n<li><strong>2008 \u2013 2011<\/strong> nEUroped: European Network for Rare Paediatric Neurological Diseases <em>(Collaborator; Head Coordinator: Tsveta Schyns, Austria)<\/em><\/li>\n\n\n\n<li><strong>2007 \u2013 2011<\/strong> RESPECT: Relating Expectations and Needs to Participation and Empowerment of Children in Clinical Trials, European Framework 7 <em>(Collaborator; Head Coordinator: Francis P Crawley, UK)<\/em><\/li>\n\n\n\n<li><strong>2007 \u2013 2009<\/strong> COST B27: Electric Neuronal Oscillations and Cognition <em>(Coordinator of the project in Slovenia and member of the managing committee in Brussels, Belgium)<\/em><\/li>\n\n\n\n<li><strong>2006 \u2013 2008<\/strong> Neuroprotective treatment after neonatal hypoxic-ischemic brain injury, Slovenian Research Agency <em>(Postdoctoral research project)<\/em><\/li>\n\n\n\n<li><strong>2004 \u2013 2007<\/strong> Follow-up of children with developmental risk factors, Slovenian Research Agency <em>(Collaborator)<\/em><\/li>\n\n\n\n<li><strong>2000 \u2013 2005<\/strong> Young Research Scientist Grant, Slovenian Research Agency<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Selected Publications<\/h2>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40684264\/\">Genotypic, functional, and phenotypic characterization in CTNNB1 neurodevelopmental syndrome<\/a><br>\u017dakelj N, Gosar D, &#8230;, <strong>Osredkar D<\/strong><br>HGG Adv. 2025 Jul 18:100483. doi: 10.1016\/j.xhgg.2025.100483. Epub ahead of print. PMID: 40684264.<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40474241\/\">Gene therapy of rare diseases as a milestone in medicine &#8211; overview of the field and report on initial experiences in Slovenia<\/a><br>Gro\u0161elj U, Kav\u010di\u010d M, &#8230; <strong>Osredkar D<\/strong>. <br>Orphanet J Rare Dis. 2025 Jun 5;20(1):279. doi: 10.1186\/s13023-025-03828-8. PMID: 40474241.<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39973463\/\">Newborn screening programs for spinal muscular atrophy worldwide in 2023.<\/a> <br>Vr\u0161\u010daj E, Dangouloff T,&nbsp;<strong>Osredkar D<\/strong>, Servais L; SMA NBS World Study Group.<br>J Neuromuscul Dis. 2024 Nov;11(6):1180-1189. doi: 10.1177\/22143602241288095.<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39949392\/\">Paving the way toward treatment solutions for CTNNB1 syndrome: a patient organization perspective.<\/a> <br>Miro\u0161evi\u010d \u0160, Khandelwal S, Amerson E, Parks E, Parks M, Cochran L, Gonz\u00e1lez Hern\u00e1ndez A, Ferraro M, Lisowski L, Perez-Iturralde A, Chung W, Jacob MH, \u017dakelj N, Lain\u0161\u010dek D, Forstneri\u010d V, Su\u0161jan P, Maruna M, Jerala R,&nbsp;<strong>Osredkar D.<\/strong> <br>Ther Adv Rare Dis. 2025 Feb 12;6:26330040251318355. doi: 10.1177\/26330040251318355. eCollection 2025 Jan-Dec.<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39626543\/\">Plant-derived cannabinoids for treatment of spasticity in children and adolescents with severe cerebral palsy: Double-blind, placebo-controlled trial.<\/a> <br>Stefanovi\u0107 M,&nbsp;<strong>Osredkar D<\/strong>, Rener-Primec Z, Peterlin J, Lapto\u0161 T, Neubauer D.Eur J Paediatr Neurol. 2024 Nov 26;54:18-24. doi: 10.1016\/j.ejpn.2024.11.007. Online ahead of print.PMID:&nbsp;39626543<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39214549\/\">Uncovering early predictors of cerebral palsy through the application of machine learning: a case-control study.<\/a> <br>Rapuc S, Stres B, Verdenik I, Lu\u010dovnik M,&nbsp;<strong>Osredkar D.<\/strong><br>BMJ Paediatr Open. 2024 Aug 30;8(1):e002800. doi: 10.1136\/bmjpo-2024-002800.PMID:&nbsp;39214549<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36293418\/\">Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature.<\/a> <br>Miro\u0161evi\u010d \u0160, Khandelwal S, Su\u0161jan P, \u017dakelj N, Gosar D, Forstneri\u010d V, Lain\u0161\u010dek D, Jerala R,&nbsp;<strong>Osredkar D.<\/strong><br>Int J Mol Sci. 2022 Oct 19;23(20):12564. doi: 10.3390\/ijms232012564.PMID:&nbsp;36293418&nbsp;<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35463898\/\">Prognostic Value of Various Diagnostic Methods for Long-Term Outcome of Newborns After Hypoxic-Ischemic Encephalopathy Treated With Hypothermia.<\/a> <br>Troha Gergeli A, \u0160kofljanec A, Neubauer D, Paro Panjan D, Kodri\u010d J,&nbsp;<strong>Osredkar D.<\/strong><br>Front Pediatr. 2022 Apr 7;10:856615. doi: 10.3389\/fped.2022.856615. eCollection 2022.PMID:&nbsp;35463898&nbsp;<\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33307321\/\">Children and young adults with spinal muscular atrophy treated with nusinersen.<\/a> <br><strong>Osredkar D<\/strong>, J\u00edlkov\u00e1 M, Butenko T, Loboda T, Golli T, Fuchsov\u00e1 P, Rohlenov\u00e1 M, Haberlova J.<br>Eur J Paediatr Neurol. 2021 Jan;30:1-8. doi: 10.1016\/j.ejpn.2020.11.004. Epub 2020 Dec 4.PMID:&nbsp;33307321<\/li>\n<\/ol>\n\n\n\n<p>For a full list of publications, visit <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Osredkar+D\">PubMed<\/a>.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:35%\">\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-nowrap is-layout-flex wp-container-core-group-is-layout-73b0033c wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"512\" src=\"https:\/\/osre.dk\/ar\/wp-content\/uploads\/2025\/02\/Damjan-Osredkar.jpg\" alt=\"\" class=\"wp-image-11\" style=\"aspect-ratio:0.75;object-fit:cover;width:272px;height:auto\" srcset=\"https:\/\/osre.dk\/ar\/wp-content\/uploads\/2025\/02\/Damjan-Osredkar.jpg 512w, https:\/\/osre.dk\/ar\/wp-content\/uploads\/2025\/02\/Damjan-Osredkar-300x300.jpg 300w, https:\/\/osre.dk\/ar\/wp-content\/uploads\/2025\/02\/Damjan-Osredkar-150x150.jpg 150w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \/><\/figure>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-left has-medium-font-size\" style=\"line-height:1.2\"><strong>Connect:<\/strong> <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=osredkar+d&amp;sort=date&amp;size=200\">PubMed<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/scholar.google.com\/citations?user=oD5iG5IAAAAJ&amp;hl=en&amp;oi=ao\">G.Scholar<\/a><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><a href=\"https:\/\/orcid.org\/0000-0002-2188-420X\">ORCID<\/a><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><a href=\"https:\/\/bib.cobiss.net\/biblioweb\/biblio\/si\/slv\/cris\/21413\">COBISS<\/a><\/li>\n\n\n\n<li class=\"has-medium-font-size\"><a href=\"https:\/\/cris.cobiss.net\/ecris\/si\/sl\/researcher\/13336\">SICRIS<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.linkedin.com\/in\/zhaval\/\" target=\"_blank\" rel=\"noreferrer noopener\">LinkedIn<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/hopnagrad.si\">Hop na Grad<\/a><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-medium-font-size\" style=\"line-height:1.2\"><strong>E-mail:<\/strong><\/p>\n\n\n\n<p class=\"has-medium-font-size\" style=\"line-height:1.2\">damjan.osredkar : kclj.si<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-medium-font-size\" style=\"line-height:1.2\"><strong>Current Address:<\/strong><\/p>\n\n\n\n<p class=\"has-medium-font-size\" style=\"line-height:1.2\">Department of Pediatric Neurology<br>University Children&#8217;s Hospital Ljubljana<br>University Medical Centre Ljubljana<br>Bohori\u010deva 20<br>1525 Ljubljana, Slovenia<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-no-title","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":29,"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":85,"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/pages\/9\/revisions\/85"}],"wp:attachment":[{"href":"https:\/\/osre.dk\/ar\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}